Additive migration levels in food simulants from polymeric materials that are intended to be into contact with food can be affected by additive stability under the migration test conditions. In this work, the stability of two plasticizers: Diethylhexyl phthalate (DEHP) and Dibutyl phthalate (DBP) was studies in aqueous food simulants A, B, C and ethanol 95% (as a substitute for olive oil- which is a fatty food simulant- simulant D), at different temperatures 20, 40 and 70 C0, during 20 days. Samples were analyzed by high performance liquid chromatography (HPLC) with UV detector. In general, DEHP and DBP plasticizers appeared to be more stable in both Ethanol (95%) and simulant C than in simulants A and B, while, they are less stable, even at low temperatures, in Simulant B than in simulant A .