Intracranial Hemorrhage Due to Vitamin-K Deficiency after the Neonatal Period


Abstract in English

Late hemorrhagic disease of the newborn (HDN) is a rare complication of vitamin-K deficiency and is especially associated with intracranial hemorrhage (ICH). It may also occur in infants after the neonatal period. This research aims to drive attention to the late form of the hemorrhagic disease of the newborn, secondary to vitamin K deficiency, as a cause of intracranial hemorrhage in young infants, after the neonatal period. A prospective study of 34 infants admitted on Pediatric Intensive Care Unit and Children Hospital at Damascus University was conducted from January 2004 to December 2004. They were diagnosed as having Late HDN by the Definite Criteria.

References used

Sutor AH.Vitamin K deficiency bleeding in infants and children. Semin Thromb Hemost. 1995;21(3):317-29
Soylu H, Aslan Y, Sari A, Erduran E. Intracerebral hemorrhage: a rare late anifestation of vitamin-K deficiency in a breastfed infant. A case report.: Turk J Pediatr. 1997 Apr Jun;39(2):265-9
Choo k E, Tan KK, Chuah SP, Ariffin WA, Gururaj A. Hemorrhagic disease in newborn and older infants: a study in hospitalized children in Kelantan, Malaysia Ann Trop Pediatr 1994; 14: 231-237

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