Effect of Aloe vacillans Leaves Extract on CCl4-induced Hepatotoxicity in Rats

This Study was designed to evaluate the effects of Aloe vacillans leaves juice on carbon tetrachloride CCl4- induced hepatotoxicity in rats. Hepatotoxicity was induced in rats by intraperitoneal (i.p) injection of CCl4 (1ml/kg) of body weight every 72h during ethanolic extract of Aloe vacillans leaves were administrated at dose 250 mg/kg and 500 mg/kg of body weight pass orally (p.o) daily for 14 days. Twenty-four hours post-CCl4 treatment, blood samples were withdrawn through retro orbital sinus.The hepatotoxicity and its prevention was assessed by serum parameters like alanine aminotransferase (ALT), aspartate aminotransferase (AST), total protein (T.P) and albumin (ALB).