Dysfunctional uterine bleeding and postmenopausal bleeding is one of the most important challenges facing gynecologists. The results of our study showed the Pipelle not to be as accurate as the standard dilatation and curettage especially in postmenopausal women after measuring the endometrial lining, we related this to the technics we used in reusing the Pipelle itself which is made for single use, and to possibly the bias of the pathologist who read the slides.