This research Paper includes a realistic vision of the possibility of Depending on (Public-Private-Partnership) (P.P.P) as an effective element of investment in the construction of (Toll Road). The research included a study of the current central road network and plans through the aspirations of the Ministry of Transport in Syria, according to the legitimate and economic trends and that will make the Private sector as a partner in infrastructure projects, including road network in Syria. The essential objective of the research is to complete what was done previously by the Ministry of Transport through (economic feasibility study of highway projects Based on B.O.T system in Syria) and detailed search in the legislative and legal framework, which is expected to be issued to cover the legal side of this mega-project which will be done according to (Public-Private-Partnership) (P.P.P), furthermore it will be the major support to the Syrian economic wheel after the current crises and studying the profits of the proposed project to investment which is a freeway from northern Syria to the south and the other one from eastern Syria to the west, an indication of the results and recommendations display.