Remote sensing technique is considered as one of the main sciences that grew very fast last years. Satellite images are important and advanced source to get data about any region on the earth. Using satellite images, integrated with geographic information system (GIS) for mapping are considered as one of the modern applications that expanded widely now a days. This paper aims at integrating the techniques of remote sensing and geographic information systems (GIS) for performing topographic study of landsat7 satellite image taken of a part of northern part of Lattakia. The two software, Erdas Imagine and ArcGIS are used to perform topographic analysis depending on digital processing for the image, then analyzing its terrain. Depending on digital terrain model (DTM), 3D slope image is derived. Land use map is written for the study area. Then, some spatial analysis are performed to find the best positions to construct different projects that have economic benefits. finally, analyses and results are discussed.