Recent studies has focused on the impact of periodontal disease on the general health like cardiovascular disease and hypertension and their interactions. We aimed to study several vascular thrombotic markers levels in patients with chronic periodontitis and hypertension. Periodontitis in hypertensives was associated with an elevation in platelets count and fibrinogen concomitantly with an increase in blood glucose levels and body mass index,in addition to greater pocket probing depth and clinical attachment loss, compared with periodontitis only.These results shed the light on periodontitis as a risk indicator for hypertension and thrombotic propensity in susceptible individuals.