The research was carried out during the growing seasons of 2011 and 2012 to study the effect of land leveling by laser, three tillage depths(01, 25 and 35cm) and three irrigation systems with 7, 8, and 9 day intervals, along with the interactive effect between them on the yield of cotton (C.V Aleppo-90), irrigation management and net grossing. The study showed the following results: 1- Land leveling by laser significantly increased the seed cotton yield, saved irrigation water, and made net grossing higher as compared to no-leveling by laser through the two seasons. 2- The two depths of tillage (25 and 35cm) significantly increased the seed cotton yield, increased the irrigation water amount, and made net grossing higher as compared to the depth of tillage (10cm).. 3- Increasing the irrigation water amount significantly increased the seed cotton yield which reached 1441KG/H, and achieved higher grossing which reached 31360 S.P/H as compared to the lower irrigation water amount. 4- The interactive effect between the factors of this experiment gave a significant positive difference. The best results were at (deep tillage 35cm × intervals 7 days × leveling by laser) through two seasons.