Effect of calyx aqueous Extract of Hibiscus sabdariffa on the levels of ALT and AST Liver Enzymes in blood serum of Local Rabbits


Abstract in English

The present study aimed to investigate the effect of calyx aqueous extract of Hibiscus sabdariffa on liver enzymes Alanine and Aspartate Transaminases (ALT and AST)level. (12) Rabbits were used and divided into two groups : (6) the experimental group and (6) control group ,the control group became distilled water , while the experimental group received aqueous extract, that was administrated orally in adose of150 mg / kg body weight (b.w.) daily for28 days .Then blood was collected each 48 hours , the serum samples were taken and prepared to the biochemical tests to determine Alanine and Aspartate Transaminases (ALT and AST)level.

References used

ABUBAKAR,M.G.;LAWAL,A.-;SULEIMAN,B.; ABDULLAHI, K Hepatorenal toxicity studies ofsubchronic Administration of calyxs of Hibiscus sabdariffa aqueous extracts in albino rats.lBayeroJourna of pure and applied sciences.3(1) (2010):16-19
AJAY,M.; CHAI, H.J.; MUSTAFA,A.M;. GILANI,A.H; MUSTAFA, M.R. - Journal of EthnopharmacologyMechanisms of the anti-hypertensive effect of Hibiscus sabdariffa L. calyces 109 (2007) 388–393
ALARCON-AGUILAR, F.J., ZAMILPA, A., PEREZ, G, M.DPERZ,A, J. CROMERO,N, E., CAMPOS,S., E.A., VAZQUEZ-C, L.I. :ROMAN,R, R. Effect of Hibiscus sabdariffa on obesity in MSG mice. Journal of Ethnopharmacology, 114 (2007).: 66-71

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