This study aimed to analyze the content of the most important social problems facing the Tishreen government universities students and Kalamoon, knowledge and compare them and arrange them according to their importance in the light of the university type, and also conceived a proposal to the role of universities to address these problems and their possible solution and improve the social and academic performance in both universities. The researcher has used descriptive analytical method which describes the phenomenon studied the quantity and quality and the method used is content analysis of the writings of students stood on the most important social problems and study tool questionnaire which is regulated and controlled in terms of the text of the question contained therein and help the researcher to develop the respondents Skjologih one condition. The results of the study can be summarized that the most important social problems are the problems of college life and Curriculum and Instruction by 57.8%, and finally came the problems related to the state of health by 3.5% of the total sample.. The study recommended to develop a comprehensive strategy at the university to cope with such problems when students and find appropriate solutions and also create a partition to follow students' problems and work to mitigate them and not close to the students and can include psychological and social structure clinic, medical clinic of the University as well as link outputs of higher education to the labor market in the local community.