Nursery ward is the safe place for premature after deliverey . It contains the basic requirements of life to him. but full of noise caused by alarms of devices, conversations of health team, ringing phones, and close the doors, exceeds what is recommended by the American Academy of Pediatrics in the Nursery wards 45 dBA (decibel A-weighting). Although it stimulates the autonomic system leading to physiologic instability like disorder in the level of oxygenation. We found in this study conducted on 30 premature with pre and post test, that the level of noise within first hour of non interventions reached 67.2 dBA, level of oxygenation inversely with noise level in it, and reduction of noise level under 45 dBA at second hour increases the oxygenation significantly. so we suggests to make reduce noise interventions within daily practices of nursing procedures, and subsequent research to study effect of noise on the rest of vital premature indicators.