Objectives: This was a prospective study, conducted to analyze the intraoperative and postoperative complications between abdominal and vaginal hysterectomy. METHODS: This study was carried out on 120 patients (85 cases abdominal and 35 cases vaginal hysterectomy),in the department of gynecology at Al-Assad university hospital in Lattakia in the period between 1/7/2013-1/7/2014. Results: the mean duration of surgery of abdominal hysterectomy was 103 min and that of vaginal was 91 min (p=0.0192). Wound infection was the main cause for febrile morbidity in abdominal hysterectomy group where as urinary tract infection was the main cause for febrile morbidity in vaginal hysterectomy. There was 3)3,5%(case of bladder injury and 2(2,8%) case of ureteric injury in abdominal hysterectomy group while none in vaginal hysterectomy group Postoperatively there was 3 (3,5%) cases of secondary haemorrage in TAH group while 1(2,8%) case in vaginal hysterectomy .there were 8 (9,4%) cases of paralytic ileus in abdominal hysterectomy while none in vaginal hysterectomy . Overall 45 (52.9%) cases of abdominal hysterectomy and 12 (34.2%) case of vaginal hysterectomy had complications (p=0.029). Conclusions: This study showed that vaginal hysterectomy was associated with less intraoperative complications and postoperative complications as compared to abdominal hysterectomy.