Cardiogenic embolism can be identified in at least 15% of ischemic stroke patients, left atrial appendage is believed to be the place where thrombi is performed, then goes to systemic circulation causing embolic accident . In this search we study the function of left atrial appendage by pulse Doppler within the proximal third of the appendage in patients with ischemic stroke. Thrombus was defined as a discrete echocardiographically dens mass within the body of atrium or the appendage, with a different echocardiographically density than the adjacent endothelium . Spontaneous echo contrast was defined as high density flow due to low flow condition , which remains stable with changes in gain setting . In conclusion , the velocities which recorded in patients with ischemic stroke were lower in comparison with other patients , and it was significant lower in patients with spontaneous echo contrast or atrial fibrillation .