The main aim of the study was to determine the frequency of coronary angiography complications with or without percutaneous coronary intervention (PCI) by the TR access compared with the TF access of patients undergoing coronary angiography (CAG). The study included 640 patients undergoing CAG with or without (PCI) in AL-ASSAD university Hospital in Lattakiabetween 1 December 2013 and 31 December 2014 .A total of 106 CAG (22.8% of all CAG) and 12 CAP (6.7% of all coronary angioplasties) were performed via a TR approach , 357 CAG (77.2% of all CAG) and 165 CAP (93.3% of all coronary angioplasties) were performed via a TF approach ,Vascular access site complications were significantly lower in the TR group than in the TF group.