Objective:This study evaluated the fluoride release of four dental restorative materials for a period of 28 days. Materials And Methods:A total of 10 specimens (4 * 2 * 2)mm3 for each of the four materials were prepared following manufacturer’s instructions and immersed independently in 2 ml of distilled water which was changed every period for all the specimens. Results:The results demonstrated that the glass ionomer cements (Fuji IX GP and VivaglassCem) release high fluoride compared with the compomer and composite resin, but rapidly decreased after the third day and continued this releasing for a period of 28 days , also showed low fluoride release of composite resin and lacking entirely with the passage of time. Conclusions:The fluoride released by the glass ionomer cements (GICs) was found to be highest during the first 24 h and decreased significantly over the 1st week with lower levels obtained on the 28th day, thus demonstrating the phenomenon of “initial burst”. The composite resin and compomer used in this study did not show this “initial burst”.