This study aimed to determine the effect of anticoccidial drug (Sulphaquinoxaline), that deployed in poultry farms in The Syrian Arab Republic, on some blood parameters, of broiler chickens for the commercial type(Ross), that available in Syria. We used drug being tested by two doses(therapeutic dose and a double therapeutic dose), as the following: (125, 250)ppm, respectively .The experience birds that braved /120/ chick at aged one day were divided to three equal distribution groups (Control, group(1), Sulphaquinoxaline, group(2) at concentration(125)ppm, Salafaquinoxaline, group(3) at concentration(250)ppm). The experience period continued for(45) days. The anticoccidial drug were presented continuously with fodder, and the blood samples were collected three times during this period. The blood samples were taken from broilers at the age(15 - 30 - 45) days. 10 samples were taken of each group from indentified three groups, then lab tests were done on the blood picture. These Tests included determination of the values of total protein, albumin and Globulin in blood serum, and also it included determination the values of some mineral elements in blood serum. These elements contained[Ca- P- Mg ] in serum.