In modern economic variables, Small and Medium-Sized Enterprises are particularly significant, necessitating their development to stay in line with these changes and to improve their competitive ability in the existing world market. This research aims to clarify and specify the role of business frames in supporting Small and Medium-Sized Enterprises in Syria. The data are collected through a pre-designed questionnaire directed to those employees, in addition to few face-to-face interviews. We have obtained some important results and offered the suggestions that contribute to the development of the performance of Small and Medium-Sized Enterprises in Syria.