Utilisation of Pentamidine as an Alternative for Pcp Prophylaxy in Hemato -Oncology Patients


Abstract in English

TMP-SMX is the first choice drug to prevent Pneumocystis jiroveci pneumonia (PCP) in hemato-oncology patients. The utilization of alternative drugs (Pentamidine – Dapsone) was suggested in some protocols in hemato-oncology. It seems that there is an increase in the utilization of alternative drugs. The aim of the study was to evaluate the utilization of different drugs to prevent PCP and to identify the reasons which lead to the utilization of alternative drugs.

References used

Shankar MS and Nania JJ . Management of Pneumocystis jirovici Pneumonia in Children Receiving Chemotherapy. Pediatr. Drugs 2007:9 (5):301-309
Carinii A. Formas de eschizogonia do Trypanozoma lewisi. Commun Soc Med Sao Palo 1910: 16:204
Kovacs JA, Gill VJ, Messnick S, et al. New insights into transmission, diagnosis, and drug treatment of Pneumocystis carinii pneumonia. JAMA 2001: 286: 2450-60

Download