ERCP is an im portant means of diagnosis and management of diseases of the biliary and pancreatic ducts, and this procedure can be associated with certain complications .This study was conducted to assess the frequency of complications following ERCP, the sample of the study consisted of 292 patients have adequate indication for ERCP. As expected, Post ERCP pancreatitis scooped the highest percentage of complications, with 3.4% (by 38.4% of all complications), While post ERCP bleeding occurred in 4 patients (1.4%). Post ERCP perforation occured in 3 patients (1.03%), Either post ERCP cholangitis had occurred in 4 patients (1.4%). Cardiac and pulmonary complications were rare (0.68 percent, 0.34%), respectively. Our study has recorded rare complication was an impaction of basket within Vatter's ampulla, that occurred in 1 patient(0.34%).