Extra-corporeal shock wave lithotripsy (ESWL) has failed to manage renal stones > 2cm in diameter. Percutaneous nephrolothotomy lithotripsy (PCNL) has proved to be a very effective alternative. This study is the first study in Syria about PCNL, reflecting our own experience. To review and to evaluate the results of percutaneous lithotripsy (PCNL) for kidney stones, especially in regard of indications, steps of the procedures and possible complications.