This research was conducted in some apiaries that Royal Jelly produce at Lattakia Governorate, which is one of the most important areas of beekeeping in Syria. This research aimed to study the investment requirements, and calculate the annual production costs, farm income indicators, and other economic indicators. In this research was used the descriptive economic analysis, data were collected of 8 apiaries, according to a form designed for this purpose, data were analyzed using appropriate statistical programs. Results showed the annual mean of royal jelly production costs, Returns, and profits in natural and additive feeding at Lattakia Governorate were 46865.5 Syrian pounds\hive, 112700 Syrian pounds\hive, 65834, Syrian pounds\hive, respectively, While net production costs, and net profits amounted to 42624.2 Syrian pounds\hive, and 8.57895 Syrian pounds\hive, respectively, and net relative income 140.50 %, also rent coefficient in relation to production costs and capital were 169.86 %, 115.16 %, respectively, and profitability coefficient in relation to production costs and capital were 140.48 %, 95.24 %, respectively, while economic efficiency, and the Payback period were 2.40, 1.05 year, respectively.