Determination of Hyoscine butyl bromide in Liquid Oral Solutions by Using HPLC-DAD
published by Damascus University
in 2013
in Chemistry
and research's language is
العربية
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Abstract in English
A simple and rapid analytical method for routine quantification of Hyoscine
butyl bromide (scopolamine butyl bromide) in liquid oral formulations by highperformance
liquid chromatography was developed and validated. The oral
solution samples can be directly analyzed by reversed-phase HPLC on Intersil
ODS-3.
References used
Tytgat GN., 2007. Hyoscine butylbromide: a review of its use in the treatment of abdominal cramping and pain; PubMed [Drugs], Volume 67, Issue 9 , pp 1343-1357
Ayman A. Gouda, 2010. Kinetic spectrophotometric determination of Hyoscine butylbromide in pure form and in pharmaceutical formulations; Arabian Journal of Chemistry, Volume 3, Issue 1, Pages 33-38
El-Saharty, Y. S., Metwaly F. H., Refaat M., El-Khateeb S. Z.; 2007. Development of membrane electrodes for the selective determination of hyoscine butylbromide, Talanta, Volume 72, Issue 2, Pages 675-681