Measuring Levels of Osteopontin in a Sample of Hepatocellular Carcinoma Patients
published by Aِl-Baath University
in 2015
in
and research's language is
العربية
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Abstract in English
Hepatocellular carcinoma (HCC) is a common malignancy and the
leading cause of death worldwide, due to late detection and high
recurrence rates. Osteopontin (OPN) has various functions,
including prevention of apoptosis and modulation of angiogenesis
which lead to tumor formation and progression, although the exact
mechanisms for the development of cancer are still unknown.
References used
CAO DX, et al. 2012 Osteopontin as potential biomarker and therapeutic target in gastric and liver cancers, World J Gastroenterol, Vol.18(30),3923-3930
SALEM M, et al. 2013 Clinical Significance of Plasma Osteopontin Level as a Biomarker of Hepatocellular Carcinoma, Gastroenterology Research, Vol.6(5),191-199
LUO X, et al. 2011 Osteopontin Stimulates Preneoplastic Cellular Proliferation Through Activation of the MAPK Pathway, Mol Cancer Res, Vol.9,1018-1029