Role of Multichannel Intraluminal Impedance( MII) and Ph Monitoring at the Same Time in Diagnosis of Gastro Esophageal Reflux Disease iIn Infants and Children Less Than 2 Years


Abstract in English

Recent studies has proved that high proportion of reflux episodes in Gastro Esophageal Reflux Disease(GERD) were non acidic ,and could not be detected by classic pH metry alone, especially less than 2 years, in whom nutrition is mainly depending on milk .It was too necessarily to improve a new technique (Multichannel Intraluminal Impedance MII) ,and by this any retrograde flow to the esophagus can be detected . The aim of this study was to determine whether pH-monitoring alone is sufficient to diagnose the Gastro Esophageal Reflux Disease (GERD),and how much the diagnosis was improved after Multichannel Intraluminal Impedance (MII) has been added to the standard pH catheter in children less than 2 years.

References used

Van Wijk,Michiel p;Benninga,Marc A et al : Role of MulticHannel Intraluminal Impedance TecHnique in Infants and CHildren.Journal of Pediatric Gastroenterology and Nutrition :January 2009-Volume 48-Issue1-p2- 12
Y van Vandenplas;Colin D Rudolph;Carlo Di Lorenzo ;et al : Pediatric Gastroesophageal Reflux Clinical Practic Guidlelines.Journal of Pediatric Gastroenterology and Nutrition. Vol 49 .No4.october 2009
Lopez Alonso M;Moya M J ;Cabo JA; et al :Twenty –four-hours esophageal impedance –PH monitoring in healthy preterm neonates:rate and characteristics of acid ,weakly acidic ,and weakly alkaline gastroesophageal reflux.Pediatrics 2006;10:10

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