The study aimed to look at the reality of the application of information and communication technology in small and medium enterprises in Syria, and stand on the most important requirements for effective use of this technology is effective. The study sample included an administrative 96 in a number of small and medium enterprises in the cities of Latakia and Tartous during the first half of 2015 represented. the most prominent results of the study that the most important requirements for activating the use of technology in institutions under consideration is the availability of qualified trained and reduce the cost of the use of technology and the development of the necessary infrastructure, In addition to the type of activity, which plays an important role in the extent of the use of technology.