The objective of this research is to find out the relationship between psychological pressure and mental toughness, and to find out the differences in these variables regarding the income and academic qualification of people who suffer from diabetes (A) in Lattakia Province. The study sample consisted of (750) diabetics, (416) males and (334) females. The ages ranged between 15 and 60 years with an average of 35 years. For this purpose, the researcher used psychological pressures scale and mental toughness scale, where their psychometric characteristics were identified through an empirical sample. The research yielded the following results: There is a statistically significant positive relationship between psychological pressure and mental toughness in the research sample. There are statistically significant differences at the indication level (0.05) between the average scores of the answers of the members of the research sample on the psychological pressure scale and mental toughness scale depending on the research's two variables: (level of income, academic qualification).