The research was conducted in Dabba site for Agricultural Scientific Research at Lattakia region in the growing season 2011 during the period from early June to mid-October. The experiment included four cultivars of peanut (ICGV 92022, C16 local 262, Souri, Al-Baladi), three row spacing (40, 60, 80 cm), and two levels of number of plants per hole-1 (one plant per hole-1, two plants per hole-1). The experiment was designed by using split-split plot design with three replications. The results of the study showed that Al-Baladi variety was superior to all other cultivars in weight pods/plant (108.8 g), weight seeds/plant (56.8 g), weight 1000 seed (914.7 g) with yield of seeds reaching (3529 kg/h). On the other hand, ICGV 92022 was superior in number of mature pods (29.22 mature pod), in number of seeds/plant (53.90 seed) and in yield (3058 kg/h). Regarding the effect of row spacing, the spacing 80 cm between rows had given the highest values significantly for yield attributes in comparison with row spacing 40 and 60 cm. Yet the highest yield per unit area obtained with row spacing was 40 cm. As about the effect of number of plants per hole-1, two plants hole-1caused significant decrease in yield attributes and significant increase in seed yield in comparison with one plant hole-1