A geological geophysical study was carried out to determine positions of gypsum Messinian (seismic reflector) at different depths on land (eastern Lattakia) and under the seabed of western Lattakia During Messinian the tectonic action changed Mediterranean Sea to evaporated basin. Northwestern Syria was affected by salinity crisis because sea water regret from it and due to that it formed lagoons. The establishment of geological sections allowed to determine reflector surface and gypsum positions by linking geological sections on land to marine seismic profiles and correlating it with drilled wells in Lattakia and seismic unites determined by (Hall et al., 2005).