A Study was conducted on a random sample of (100) cases of pregnancies with preterm labour admitted to Al-Assad University Hospital Obstetrics and Gynecology section Lattakia during the period April 2012 until April 2013. The efficiency of using nifedipine for inhibiting pre-term labour was studied together with the side effects during treatment and the cost of using nifedipine comparable to using another tocolysis. The percentage of success in using nifedipine for inhibiting preterm labour by 60 m.g method during the first 24h was (78.5%) while it was (81.1%) by 90 m.g method for the same period. The percentage of side effects was (19.7%) of which headaches were the most recurrent (50%). Using oral nifedipine costs less than using intravenous Salbutamol used to inhibit preterm labour at Al-Assad University Hospital.