Our study included 40 patients with a single length of less than 1 cm Urethral Stricture, between the ages of (20-75) years, reviewed the Assad University Hospital (Urinary clinic and Emergency Room) in Latakia between 2011 - 2012. Patients were distributed in two groups (A)-(B). The first group were treated using the technique of laser helium. The second group treated using a cold knife (a traditional biopsy). Patients were distributed in both groups without any considerations or statistical differences in the Pathogenicity mechanism, the stricture site, or any clinical diseases caused by them, but that all patients have a a single Urethral Stricture that does not exceed a length of 1 cm. The effectiveness of treatment were then evaluate using Uroflowmetry, where all patients was conducted to measure the rate of flow of urine before treatment and after treatment at 3 months and then after 6 months. Statistical study showed clear differences in the efficiency of treatment in favor of laser Urethrotomy(0,05> P). As we compare our results with three global studies and pointed to the compatibility with sites.