This paper, we evaluated some varieties of local cheeses. samples were collected randomly from various production sites in Homs. Chemical and microbiological analyses were applied to determine their suitability to the Syrian standards. This study shows that 54% of Baladi cheese samples, 25% of Akkawi(Cows), 18% of Akkawi(Sheep), 12% of Kashkawan ,2 %of Chelal samples, that 2% of Halloumi cheese samples, and 8% of Msannara cheese samples contained Escherichia coli bacterium. This results also indicate that 15% of Baladi cheese samples, 12% of Akkawi(Cows), 8% of Kashkawan cheese,4 %of Chelal cheese, and 8% of Msannara samples contained Staphylococcus aureus bacteria. As well as the percentage of Baladi cheese samples containing Salmonella bacteria was 8%, and Akkawi(Cows) cheese samples was 4%, and 2% in Msannara cheese samples. This study indicated that local cheeses have no uniform or standardized chemical characteristics. This study shows that 67% of Baladi cheese samples, 33% of Akkawi(Cows), 83 %of Chelal , and 100% of Kashkawan samples were contrary to the Syrian Normal Standard for dry matter. And all samples of cheese identical to the Syrian Normal Standard for sodium chloride 100%.