This research addresses the definition of industrial cities and the properties and characteristics of composition of industrial cities as industrial cities one of the major sources of agglomeration economics and external economics . The research addresses definition Syrian industrial cities and geographical distribution, and its mission statement and purpose The study and analysis of the reality of investing in Syrian industrial cities of through the study and analysis of a set of indicators/investment size-the number of the plants under construction-the number of plants in production-the number of workers in the construction and operation of laboratories-the number of foreign firms and joint-Arabic and investment income The research addresses the subject of direct and indirect damage caused to the direct investments of the four industrial cities in Syria because of the current crisis The search finds a set of results and some recommendations about the industrial cities.