The Shanghai Cooperation Organization (SCO) is considered relatively a modern regional organization which was announced officially in 2001; it included all of China, Russia, Kazakhstan, Uzbekistan, Tajikistan and Kyrgyzstan (as permanent members, the (SCO) occupied a very important position in the world several years ago, via the capacities of its countries in economic, political and military forces. In the light of the current crisis afflicting Syria and the pressures and foreign sanctions upon it, in addition to the new strategy adopted by the Syrian government, which stipulates "going east", the Shanghai Cooperation Organization shaped broad international scope for Syria to get rid of the pressure and Western sanctions. This research will try to shed light on the (SCO) and its attitude toward Syrian crisis and the implications of the stands of some countries, especially China and Russia