The goal of this work is finding exact solitary wave solutions to generalized Fitzhug-Nagumo equation with constant coefficients, by using the exp-function method, where we have illustrated graphically one of them, the obtained results, with aid of symbolic programs as Maple and Mathematica, show that this method is simple, direct and very efficient for solving this kind of nonlinear PDEs, and it requires no advanced mathematical knowledge, so it is convenient to scientists and engineering.