Inflammatory Breast Cancer Management


Abstract in English

A retrospective study included 25 cases with inflammatory breast cancer. The patients were admitted to AL-Assad University Hospital, Lattakia, Syria (average age 55, and range 49-61 years old). The most common clinical signs and symptoms were: erythema 100%, edema 100%, enlarged axillary nodes 100%, Nipple flattened/inverted 96%, warm Breast 92%, Ridges/thickening of breast 84%, Peau d’orange 88%, painful/tender Breast 88%, and Mass 80%. Mammography findings were: an increase in skin thickness 100%, an increased tissue density in the involved breast 100%, and an asymmetric widening of the sub-cutaneous lymphatic vessels 33.33%. 80% of cases were diagnosed as stage IV. All patients received primary neoadjuvant chemotherapy for three cycles. After that a modified radical breast mastectomy and axillary lymph nodes dissection were performed for all patients. The wound edges were closed primarily after dissecting the skin in 76%, for 4 patients 16% a split-thickness skin grafts were performed, and for 2 patients 8% a Latissimus dorsi pedicled myocutaneous flap was performed.

References used

HAAGENSEN, C. Diseases of the breast. 2nded, Saunders, Philadelphia, 1971, p. 576–84
LEVINE PHš STEINHORN SC. Inflammatory breast cancer The experience of the Surveillance, Epidemiology, and End Results (SEER) program. Journal of the National Cancer Institute U.S.A.Vol.74,N°.2, 1985,291–7
CHANG Sš PARKER SL. Inflammatory breast carcinoma incidence and survival: the Surveillance, Epidemiology and End Results program of the National Cancer Institute, 1975–1992. Cancer U.S.A.Vol.82,N°12, 1998,2366–72
BELL C. A system of operative surgery. 2nded, Hale and Hosmer ,Hartford, 1814. p. 136
LEE BJšTANNENBAUM NE. Inflammatory carcinoma of the breast: a report of twenty-eight cases from the breast clinic of the Memorial Hospital. Surgery, Gynecology & Obstetrics U.S.A.Vol.39,N°1, 1924,580–95

Download