Celiac Disease as a Risk Factor of Anemia in Children
published by Tishreen University
in 2014
in Medicine
and research's language is
العربية
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Abstract in English
This study included 502 children between 0,5-15 years old. They were all subjected to duodenal biobsy for several reasons, and underwent investigations; Hb, MCV, MCH, MCHC and RDW.
The prevalence of celiac disease among anemic children was higher than nonanemic patients (36,04% vs 12,14%). The mean duration of compliance was higher in both anemic children and celiac patients than in comparing groups .The mean levels of Hb,MCV,MCH and MCHC were lower in celiac group, while RDW was higher. Anemia was the most common presentation of celiac disease and it was seen in 77% among celiac children, while failure to thrive was detected in 43% of celiac group. Clinicians should consider celiac disease as a possible cause of anemia in all subjects with unexplained or refractory anemia
References used
Hill I.D;Dirk M.H;Liptak G.S;et al(2005) . Guideline for the diagnosis and treatment of celiac disease in children: recommendations ofthe North American Society for Pediatric Gastroenterology,Hepatology and Nutrition.JPGN;40:1-19
ROBIN S.G(2004).Advances in celiac disease .Curr Opin Gastroenterol.;20:95- 103.Pubmed-Medline
Tesei N,Sugai E,Vazquez H,Smecuol E,Niveloni S,Mazure R,et al(2003).Antibodies to human recombinant tissue transglutaminase may detect coeliac disease patients undiagnosed by endomysial antibodies.Aliment Pharmacol Ther;17:1415- 23.Pubmed-Medline
CACCIARI,E;SALARDI,S;LAZZARI,R;COLLINA,A;BIASCO(2003).Clinical Gastroenterology and Hepatology.American Journal of Haematology1,Vol 93,Issue 12, ,1785-1791
Abdulkarim A.S,Murray J.A(2003).The diagnosis of coeliac disease.AlimentPharmacol Ther;17:987-95.Pubmed-Medline