Our study included (84) patients: 86 cases suffering from chronic osteomyelitis: various causes, location and degrees. All patients operated: after curettage of necrotic and infected tissues; system of continuous irrigation with antibiotics was inserted to the infected zone; all cases were followed up for 1 year. 86% of positive results were obtained and results were bad in 14% of cases> The high positive results (86%) confirm high effect of continuous irrigation with antibiotics as a good method for chronic osteomyelitis treatment, because this method allows delivery of suitable antibiotics in high concentration into the infected area, which is enough to kill microbes and allows to obtain best results.