The research aims to identify the role of organizational culture in reducing resistance to change of the employees through a study of the relationship between the dimensions of the organizational culture, and the reasons of resistance change by employees working in Lattakia City Council. To achieve the objectives of the research, a questionnaire was designed and distributed to (343) employees in Lattakia City Council, (315) questionnaire were complete and valid for statistical analysis, with a response rate of (91.84%). Relying on multiple regression, the following results were reached: 1. There is a strong inverse relationship which is statistically significant between the elements after the containment and interdependence of (empowerment, staff development, teamwork and participation), and a reeducation of the resistance of workers to change, wherever after containment and coherence elements are available, there is a decline in the causes resistance of workers to change. 2. There is strong inverse relationship that is statistically significant between the elements after the consistency and uniformity of working (core values, agreement, coordination and integration), and a reduction of resistance workers to change, i.e. when elements after consistency and homogeneity are availed, they lead to a decline in the causes of workers resistance to change. 3. There is strong inverse relationship which is statistically significant between the elements of the human aspects (respect and appreciation, justice, encouragement achievement, and social welfare), and the reeducation of workers resistance to change, i.e., whenever there are elements of the human aspects, there is a decline of the causes of workers resistance to change. 4. There is strong inverse relationship which is statistically significant between the elements after the organizational climate of (administrative practices, rewards, communications, and surveillance system), and the reduction of workers resistance to change, i.e., wherever after the organizational climate elements are available, there is a decline in the causes of workers resistance to change.