We present our development of the multilingual machine translation system for the large-scale multilingual machine translation task at WMT 2021. Starting form the provided baseline system, we investigated several techniques to improve the translation quality on the target subset of languages. We were able to significantly improve the translation quality by adapting the system towards the target subset of languages and by generating synthetic data using the initial model. Techniques successfully applied in zero-shot multilingual machine translation (e.g. similarity regularizer) only had a minor effect on the final translation performance.