The influence of the mutual interaction between the two outgoing nucleons (NN-FSI) in electro- and photoinduced two-nucleon knockout from $^{16}O$ has been investigated perturbatively. It turns out that the effect of NN-FSI depends on the kinematics and on the type of reaction considered. The effect is generally larger in pp- than in pn-knockout and in electron induced than in photoinduced reactions. In superparallel kinematics NN-FSI leads in the $(e,epp)$ channel to a strong increase of the cross section, that is mainly due to a strong enhancement of the $Delta$-current contribution. In pn-emission, however, this effect is partially cancelled by a destructive interference with the seagull current. For photoreactions NN-FSI is considerably reduced in superparallel kinematics and can be practically negligible in specific kinematics.