Measurements of open charm hadro-production from CERN and Fermilab experiments are reviewed, with particular emphasis on the absolute cross sections and on their A and sqrt(s) dependences. Differential pt and xf cross sections calculated with the Pythia event generator are found to be in reasonable agreement with recent data. The calculations are scaled to nucleus-nucleus collisions and the expected lepton pair yield is deduced. The charm contribution to the low mass dilepton continuum observed by the CERES experiment is found to be negligible. In particular, it is shown that the observed low mass dilepton excess in S-Au collisions cannot be explained by charm enhancement.
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