Based on the intermediate energy radioactive Ion Beam Line in Lanzhou (RIBLL) of Heavy Ion Research Facility in Lanzhou (HIRFL) and Low Energy Radioactive Ion Beam Line (GIRAFFE) of Beijing National Tandem Accelerator Lab (HI13), the radioactive ion beam physics and nuclear astrophysics will be researched in detail. The key scientific problems are: the nuclear structure and reaction for nuclear far from $beta$-stability line; the synthesize of new nuclides near drip lines and new super heavy nuclides; the properties of asymmetric nuclear matter with extra large isospin and some nuclear astro- reactions.