In strong dynamical schemes for electroweak symmetry breaking the third generation must be treated in a special manner, owing to the heavy top quark. This potentially leads to new flavor physics involving the members of the third generation in concert with the adjoining generations, with potential novel effects in beauty and charm physics. We give a general discussion and formulation of this kind of physics, abstracted largely from Topcolor models which we elaborate in detail. We identify sensitive channels for such new physics accessible to current and future experiments.