No Arabic abstract
The conformation and scaling properties of self-avoiding fluid vesicles with zero extrinsic bending rigidity subject to an internal pressure increment $Delta p>0$ are studied using Monte Carlo methods and scaling arguments. With increasing pressure, there is a first-order transition from a collapsed branched polymer phase to an extended inflated phase. The scaling behavior of the radius of gyration, the asphericities, and several other quantities characterizing the average shape of a vesicle are studied in detail. In the inflated phase, continuously variable fractal shapes are found to be controlled by the scaling variable $x=Delta p N^{3 u/2}$ (or equivalently, $y = {<V>}/ N^{3 u/2}$), where $N$ is the number of monomers in the vesicle and $V$ the enclosed volume. The scaling behavior in the inflated phase is described by a new exponent $ u=0.787pm 0.02$.
Soft bodies flowing in a channel often exhibit parachute-like shapes usually attributed to an increase of hydrodynamic constraint (viscous stress and/or confinement). We show that the presence of a fluid membrane leads to the reverse phenomenon and build a phase diagram of shapes --- which are classified as bullet, croissant and parachute --- in channels of varying aspect ratio. Unexpectedly, shapes are relatively wider in the narrowest direction of the channel. We highlight the role of flow patterns on the membrane in this response to the asymmetry of stress distribution.
While the behavior of vesicles in thermodynamic equilibrium has been studied extensively, how active forces control vesicle shape transformations is not understood. Here, we combine theory and simulations to study the shape behavior of vesicles containing active Brownian particles. We show that the combination of active forces, dimensionality and membrane bending free energy creates a plethora of novel phase transitions. At low swim pressure, the vesicle exhibits a discontinuous transition from a spherical to a prolate shape, which has no counterpart in two dimensions. At high swim pressure it exhibits stochastic spatio-temporal oscillations. Our work helps to understand and control the shape dynamics of membranes in active-matter systems.
The steady motion and deformation of a lipid-bilayer vesicle translating through a circular tube in low Reynolds number pressure-driven flow are investigated numerically using an axisymmetric boundary element method. This fluid-structure interaction problem is determined by three dimensionless parameters: reduced volume (a measure of the vesicle asphericity), geometric confinement (the ratio of the vesicle effective radius to the tube radius), and capillary number (the ratio of viscous to bending forces). The physical constraints of a vesicle -- fixed surface area and enclosed volume when it is confined in a tube -- determine critical confinement beyond which it cannot pass through without rupturing its membrane. The simulated results are presented in a wide range of reduced volumes [0.6, 0.98] for different degrees of confinement; the reduced volume of 0.6 mimics red blood cells. We draw a phase diagram of vesicle shapes and propose a shape transition line separating the parachute-like shape region from the bullet-like one in the reduced volume versus confinement phase space. We show that the shape transition marks a change in the behavior of vesicle mobility, especially for highly deflated vesicles. Most importantly, high-resolution simulations make it possible for us to examine the hydrodynamic interaction between the wall boundary and the vesicle surface at conditions of very high confinement, thus providing the limiting behavior of several quantities of interest, such as the thickness of lubrication film, vesicle mobility and its length, and the extra pressure drop due to the presence of the vesicle. This extra pressure drop holds implications for the rheology of dilute vesicle suspensions. Furthermore, we present various correlations and discuss a number of practical applications.
We present a new study of the form factors for D -> K semileptonic decay from lattice QCD that allows us to compare the shape of the vector form factor to experiment and, for the first time, to extract V_cs using results from all experimental q^2 bins. The valence quarks are implemented with the Highly Improved Staggered Quark action on MILC configurations that include u, d and s sea quarks. The scalar and vector currents are nonperturbatively normalised and, using phased boundary conditions, we are able to cover the full q^2 range accessible to experiment. Our result is V_cs = 0.963(5)_{expt}(14)_{lattice}. We also demonstrate that the form factors are insensitive to whether the spectator quark is u/d or s, which has implications for other decay channels.
Within the framework of the Helfrich elastic theory of membranes and of differential geometry we study the possible instabilities of spherical vesicles towards double bubbles. We find that not only temperature, but also magnetic fields can induce topological transformations between spherical vesicles and double bubbles and provide a phase diagram for the equilibrium shapes.