We present the result of direct leptoquark searches based on 110 pb-1 of integrated luminosity collected by the Collider Detector at Fermilab during the 1992-93 and 1994-95 Tevatron runs at sqrt{s}=1.8 TeV. We present upper limits on the production cross sections as a function of the leptoquark mass. Using the NLO calculation of the leptoquark-pair production cross sections we extract lower-mass limits for first, second and third generation leptoquarks. We also present the result of an indirect search for Pati-Salam leptoquarks via exclusive e-mu decay modes of B^{0}_{s} and B^{0}_{d}.
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