We examine the effects of significant electron anti-neutrino fluxes on hydrogen burning. Specifically, we find that the bottleneck weak nuclear reactions in the traditional pp-chain and the hot CNO cycle can be accelerated by anti-neutrino capture, increasing the energy generation rate. We also discuss how anti-neutrino capture reactions can alter the conditions for break out into the rp-process. We speculate on the impact of these considerations for the evolution and dynamics of collapsing very- and super- massive compact objects.