We present the first large-scale radiative transfer simulations of cosmic reionization, in a simulation volume of (100/h Mpc)^3, while at the same time capturing the dwarf galaxies which are primarily responsible for reionization. We achieve this by combining the results from extremely large, cosmological, N-body simulations with a new, fast and efficient code for 3D radiative transfer, C^2-Ray. The resulting electron-scattering optical depth is in good agreement with the first-year WMAP polarization data. We show that reionization clearly proceeded in an inside-out fashion, with the high-density regions being ionized earlier, on average, than the voids. Ionization histories of smaller-size (5 to 10 comoving Mpc) subregions exibit a large scatter about the mean and do not describe the global reionization history well. The minimum reliable volume size for such predictions is ~30 Mpc. We derive the power-spectra of the neutral, ionized and total gas density fields and show that there is a significant boost of the density fluctuations in both the neutral and the ionized components relative to the total at arcminute and larger scales. We find two populations of HII regions according to their size, numerous, mid-sized (~10 Mpc) regions and a few, rare, very large regions tens of Mpc in size. We derive the statistical distributions of the ionized fraction and ionized gas density at various scales and for the first time show that both distributions are clearly non-Gaussian. (abridged)