We present an analysis of the properties of the hot interstellar medium (ISM) in the merging pair of galaxies known as The Antennae (NGC 4038/39), performed using the deep, coadded ~411 ks Chandra ACIS-S data set. These deep X-ray observations and Chandras high angular resolution allow us to investigate the properties of the hot ISM with unprecedented spatial and spectral resolution. Through a spatially resolved spectral analysis, we find a variety of temperatures (from 0.2 to 0.7 keV) and Nh (from Galactic to 2x10^21 cm^-2). Metal abundances for Ne, Mg, Si, and Fe vary dramatically throughout the ISM from sub-solar values (~0.2) up to several times solar.