We consider spherical stellar clusters with a broad mass function and a relaxation time short enough so that the segregation of massive stars toward the centre occurs before they have time to evolve off the main sequence. The relaxational and collisional dynamics of model clusters is followed with a high-resolution Monte Carlo code. Stellar collisions are treated in a realistic way, through the use of a outcome of a very large set of SPH simulations. We find that, even in proto-galactic nuclei models with high velocity dispersions, run-away growth of a very massive star (VMS, M>100 M_sun) occurs in all cases when the core collapse time is shorter than the MS life time of massive stars, i.e. 3 Myrs. The VMS is a likely progenitor for an intermediate-mass or massive black hole (IMBH/MBH).
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