(Abridged) We present R-band images covering more than 11 square degrees of sky obtained with the KPNO 4-m telescope in preparation for the Spitzer Space Telescope First Look Survey. The FLS was designed to characterize the mid-infrared sky at depths 2 orders of magnitude deeper than previous surveys. The extragalactic component is the first cosmological survey done with Spitzer. Two relatively large regions of the sky were observed: the main FLS extra galactic field (17h18m+59d30m) and ELAIS-N1 field (16h10m+54d30m). The overall quality of the images is high. The relative astrometric accuracy is better than 0.1 and the typical seeing is 1.1. Images are relatively deep since they reach a median 5-sigma depth limiting magnitude of R=25.5 (Vega). Catalogs have been extracted using SExtractor using thresholds in area and flux for which the number of false detections is below 1% at R=25. Only sources with S/N greater than 3 have been retained in the final catalogs. Comparing the galaxy number counts from our images with those of deeper R-band surveys, we estimate that our observations are 50% complete at R=24.5. These limits in depth are sufficient to identify a substantial fraction of the infrared sources which will be detected by Spitzer.